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The overall lower total organic content for the FA-conjugated material (30%) compared with the non-conjugated drug-loaded SBA-15 (50%) implies that conjugation reduced the amount of physically adsorbed (free) drug for example by replacing weakly adsorbed drug with covalently tethered folic-aciddrug species or by additional washing steps removing unbound drug

Selective estrogen receptor modulators (SERMs) like raloxifene have demonstrated variable effects, with some reducing lesion size in preclinical models but limited clinical applications due to scarce and low-quality evidence

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doi: 10.1046/J.1365-2222.2002.00532.X 139 The role of disturbances of lipid metabolism in pathogenesis of allergic rhinitis