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Amlodipine reacts with different cellular regulators, e.g., mitogen-activated protein kinases (MAPKs), transcription factors, and cell cycle proteins, which may affect the maintenance of pancreatic -cell function and insulin sensitivity and control the cellular reply to oxidative stress and abnormal protein synthesis induced by AGEs 95

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Selection of high-transition temperature Phospholipids (HSPC, DPPC, or DOPE) to create rigid, oxygen-barrier bilayers