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These questions become especially important when a therapy has not yet completed the FDA approval process

If neurographic abnormalities are detected in an asymptomatic subject and even with normal Vit B12 levels, we suggest starting B12 supplementation if LCIG infusion has to be started

Similar to weight-gain products such as Apetamin, these products are likely being marketed via social media accounts

(2) the specific CI inhibitor IACS-010759 was recently reported to promote neurotoxicity, making this an unattractive agent for combination therapy in CRC given the neurotoxicity long-recognized with oxaliplatin treatment 51