can semaglutide cause ed Comparative safety and side effects of and tirzepatide: Implications for clinical decision-making in obesity management NW Integrative Medicine: Semaglutide Treatment

Important safety considerations include a boxed warning for thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), risk of pancreatitis, gallbladder disease, and acute kidney injury with dehydration

The SURMOUNT-1 trial showed average weight loss of 20.2 percent at 72 weeks on the highest dose, a figure that stunned the medical community when it was first published

Healthcare professionals may also prescribe it off-label to help with weight loss in people who have overweight or obesity

Hathaway JT, Shah MP, Hathaway DB, Zekavat SM, Krasniqi D, Gittinger JW Jr, Cestari D, Mallery R, Abbasi B, Bouffard M, Chwalisz BK, Estrela T, Rizzo JF