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Primary applications include treating B12 deficiency, supporting energy production, and maintaining neurological health

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To investigate whether the increased GSH level at 100 g/ml 5-FOA (Figure S2A) was stable during longer-term cultivation of the modified strain, cellular GSH content was monitored every 10 generations during sequential batch cultivation in flasks at 100 g/ml 5-FOA (after every ~ 10 generations, aliquots of overnight culture were transferred to fresh medium giving OD 0.01 and re-incubated)

The peptide incorporates specific amino acid substitutions at key positions to enhance stability against enzymatic degradation while preserving high affinity for the GHRH receptor