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This has prompted adaptations in the food sector and significant shifts in the weight loss industry

Recent studies have uncovered increased DPP-4 expression and secretion from hepatocytes in obese mice, with a DPP-4 expression and activity much higher in the liver than in adipose tissue, indicating its emerging role as a hepatokine in the interplay between hepatocytes and adipocytes [4]

Crucially, the weight loss trajectory at 26 weeks had not plateaued suggesting that longer treatment duration would produce further reductions

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