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Common Side Effects of Glutathione Supplementation While glutathione is generally well-tolerated, some individuals may experience side effects after supplementation

The current clinical evidence of intravenous glutathione for skin lightening is limited to a single study with a dubious study design and apparently flawed analysis of results, casting doubt on the drug's efficacy and reported adverse effects, with no evidence to prove its efficacy.There was only one placebo-controlled study on intravenous glutathione showing 37.5% response versus 18.7% placebo, and IV glutathione is contraindicated due to lack of efficacy and side effects

Bakis-Petsoglou S, Le Guay JL, Wittal R

Pflipsen MC, Vega Colon KM (2020): Anaphylaxis: recognition and management