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The only difference is the change of the leaving group from ROH to RNH 3 +

In the debate Nadine Dorries incorrectly uses the terms Prescription, Pharmacy/Over the Counter and General Sales but ultimately the point is that in order for the MHRA to move a medicine from one category to another it must be shown that the medicine does not present a direct or indirect danger to human health, even when used incorrectly, if used without the supervision of a doctor, or is not frequently and to a very wide extent used incorrectly, and as a result is not likely to present a direct or indirect danger to human health

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Targeting ABL-IRE1alpha Signaling Spares ER-Stressed Pancreatic Beta Cells to Reverse Autoimmune Diabetes