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Furthermore, a study demonstrated that lacosamide administered to epileptic patients reduced the levels of isoprostanes in urine samples (76) and this study favors our finding of reduced isoprostanes levels by lacosamide in the extracellular hippocampal region

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Rodrigues-Pinto, R., Richardson, S

However, the subsequent secondary injury arising minutes to months after the initial insult exacerbates the neuropathology through various cellular processes, including neuroinflammation, oxidative stress, metabolic dysfunction, and excitotoxicity (Walker and Tesco, 2013)