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According to the Joi + Blokes GLP-1 page, compounded medications are "produced in licensed facilities and regulated by state Boards of Pharmacy." The company identifies five partner pharmacies by name and location in its terms of service

When it circulated in Britain in the late 2000s, the drug was called the tan jab, and also referred to as the Barbie drug. A 2024 study in the Journal of European Dermatology and Venereology noted that Melanotan IIs use has been linked to rare instances of rhabdomyolysis, a potentially deadly muscle-breakdown syndrome, and priapism (the type of painful, unending erection Viagra ads warn you about)

Oxidized low-density lipoprotein associates with cardiovascular disease by a vicious cycle of atherosclerosis and inflammation: A systematic review and meta-analysis

If it worsens or lasts more than a few days, consult a healthcare provider