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The synthetic Ang-(17) analog AVE 0991 inhibits this pathway, alleviating liver damage [37]

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After 24 h culture, the transfected cells were seeded into 384-well microtiter plates at a density of 3,000 cells per well in HBSS supplemented with 5 mM HEPES, 0.1% (w/v) BSA or 0.1% (w/v) casein and 0.5 mM 3-isobutyl-1-methylxanthine

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These effects were associated with microparticle formation, an important biomarker of endothelial cell damage and apoptosis 22 as well as cell activation and proliferation

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