Their approach includes the use of GLP-1 DNA complexes with linear polyethylenimine (lPEI), coated with a mixture of a neutral lipid, dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and 1,2-dimyristoyl-rac-glycero-3-methoxy poly (ethylene glycol)-200 (DMG-PEG), which would render the nanoparticles hydrophilic and electrostatically neutral
Huang YS, Chen Z, Chen YQ, Ma GC, Shan JF, Liu W, Zhou LF (2008) Preparation and characterization of a novel Exendin-4 human serum albumin fusion protein expressed in Pichia pastoris
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