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A 2025 joint advisory issued by the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and the Obesity Society recommended that individuals undergoing active weight reduction aim for 1.2 to 1.6 grams of protein per kilogram of body weight daily, with some experts suggesting that setting an absolute target of 80 to 120 grams per day may enhance adherence while ensuring adequate intake (Mozaffarian et al.)

The study demonstrated for the first time that the C718T polymorphism in the 3-untranslated region of the GPX4 gene could be considered as a genetic marker of susceptibility to CS in patients with EH