Some HH cases with pancreatitis were treated with surgery in the past [13, 14, 17, 24], but in other cases, physicians chose conservative treatment including administration of intravenous fluids, pain killers, and diet as tolerated because of high risk of surgery [15, 16] or patients refusal to undergo operation [16, 18,19,20,21]
As more studies are completed and additional approvals are received, these therapies are becoming part of treatment for a wider range of health conditions
Moreover, a serious limitation with these datasets is the lack of sufficient patient level data to assess key variables, including other PDAC risk factors (particularly diabetes and obesity) as well as dosing and duration of drug exposure
This asymmetric logistics planning is a recurring theme in Wolverine stack dosage protocol design