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These medications are not recommended for individuals who are pregnant, have a history of eating disorders, pancreatitis, or unmanaged gastrointestinal conditions such as heartburn, acid reflux, gastroparesis, Celiac disease, or Crohns Disease

A qualified clinician should review the patients diagnosis, conventional options, medications, allergies, pregnancy status when relevant, organ function, prior reactions, goals, and ability to participate in monitoring

The outcome is decreased circulating FFAs following surplus caloric intake, limiting lipid spillover into ectopic regions and improvement in systemic insulin sensitivity [45]

GarberAJAbrahamsonMJBarzilayJIBlondeLBloomgardenZTBushMAet al