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Axxams metabolic platform assays Enteroendocrine cells act as nutrient sensors in the gut, detecting dietary components through receptors located on their luminal surface

They compared how the drug is metabolized by the different strains and looked for variations in gene expression and changes in endogenous metabolites in response to acetaminophen administration

10.1016/j.bioorg.2004.06.005 61 RabahiF.BrlS.SiroisJ.BeckersJ

RNA sequence analysis and differentially expressed genes After observing that there were no genetic mutations and that growth rate and lag time were altered, possibly indicating a change in fitness, RNA-Seq was performed to see if Zn pre-exposed samples had differential gene expression profiles on the transcript level compared to a WT control sample (passaged in zinc-free media for 5 days)