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We have demonstrated the beneficial effect of G49, a dualAG, in resolving metabolic-dysfunction associated steatohepatitis (MASH) and improving liver regeneration under this pathological condition in C57BL/6J mice by targeting multiple homeostatic mechanisms including inflammation, oxidative/endoplasmic reticulum stress, mitochondrial dysfunction, and shifting glucose metabolism 13

Finally, there was an overall decrease in apoptosis of hepatocytes pretreated with CAPE, suggesting it may have anti-apoptotic properties [47]

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Since Vitamin B12 is water-soluble, excess amounts are typically excreted through urine