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Concluding remarks An ideal COVID-19 vaccine target would be expected to induce high titres of nAbs, reduce non-nAb production to minimize ADE potential, elicit robust T H 1 cell-biased responses but low T H 2 cell-biased responses to lower the ERD potential, maintain long-lasting immunological memory, and provide cross-protection between CoVs

The length of ICU stays and the need for endotracheal intubation were also documented and daily venous blood samples were taken for seven consecutive days to assess the levels of D-dimmer, lactate dehydrogenase (LDH), and CRP

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