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In a polymicrobial model of sepsis induced by cecal ligation and puncture, a GLP-1 analog ameliorated vascular inflammation and oxidative stress by improving endothelial function ( In a cardiac fibrosis model, the GLP-1 analogue liraglutide reduced vascular reactivity, cardiac hypertrophy, fibroblast accumulation, collagen deposition and MCP-1 production (40)