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Thickened skin : In advanced cases, skin may thicken and become bumpy, particularly on the nose (rhinophyma)

Subsequently, Erastin-induced pregnant rats exhibited a lower embryo survival rate, fetal growth restriction (FGR), and reductions in placental diameter and weight compared to the Sham group (Fig

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53 Although dementia was not a primary outcome, a pooled analysis of 15,820 patients with type 2 diabetes randomised to GLP-1 receptor agonist treatment or placebo found a 50% reduction in dementia progression over a median of 3.6 years (15 cases in the placebo group vs 32 in the GLP-1 receptor agonist group)