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Conclusions In this study, we present a robust and integrative virtual screening strategy for the identification of agonists of the GLP-1R

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Its main function is to assist long-chain fatty acids in undergoing beta-oxidation, facilitating the body's utilization of fat, including burning excess fat for energy, without side effects

This lipidation promotes albumin binding, extending its plasma half-life to approximately one week, which allows for once-weekly dosing