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For intermediate-risk patients, hydration plus the uric acid-lowering drug allopurinol (Zyloprim) or rasburicase (Elitek), is recommended to prevent TLS
These changes help cells survive and grow, but the root cause of cancer remains the accumulation of genetic mutations that disrupt normal growth control. These mutations can affect multiple metabolic pathways, which explains why enzymes like NAMPT are altered
The EC layer is composed of TJs, which consist of occludin and claudin
Advances in nanotechnology-based delivery systems offer promising solutions to these limitations
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