Results are inconsistent and slow 1
Table I [i] PIO pioglitazone, GLP-1R glucagon-like peptide 1 receptor, SGLT2 sodium-glucose co-transporters 2, TOFO tofogliflozin, SUL sulfonylurea, MET metformin, DAPA dapagliflozin, EXE exenatide, NAFLD non-alcoholic fatty liver disease, T2D type 2 diabetes, A1C glycated hemoglobin, ALT alanine aminotransferase, AST aspartate aminotransferase, -GT gamma-glutamyl transferase, MRI-PDFF MRI-proton density fat fraction, MRE-LSM MR elastography-liver stiffness, RCT randomized controlled trial, EDICT Efficacy and Durability of Initial Combination Therapy, CAP controlled attenuation parameter, LSM liver stiffness measurement, BMI body mass index
The real question is whether this space will mature into a legitimate, responsible arm of obesity medicine or be dismissed as a chaotic market of pill mills
Multiple forms of long-term synaptic plasticity at hippocampal mossy fiber synapses on interneurons