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Yes, they are generally very safe when given by trained professionals

High concentrations of 4HNE have been associated with different processes such as apoptosis, cell differentiation, altered gene expression and with several diseases correlated to redox imbalance such as neurodegenerative and cardiovascular diseases, metabolic syndrome, and cancer 15

In addition to human breast tumors, IFP increases in experimental models of breast cancer, such as severe combined immunodeficient mice bearing highly invasive, triple-negative MDA-MB-231 human breast cancer tumors [20] and BN472 rat mammary carcinomas [21]

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