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Barroso, O., Schamasch, P

The compounds identified were galangin, kaempferide, -sitosterol, 1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3,5-heptanediol, 5-hydroxy-7-(4-hydroxyphenyl)-1-phenyl-3-hepta none, 3- O --D-6-palmitoylgluco side (3 R ,5 R )-1-(4-hydroxyphenyl)-7-phenyl-3,5-heptanediol, (5R)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-3-heptanone, and 5-hy droxy-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-3-hept anone (Shin et al., 2002)

It can, and the article flags this specifically for people also taking insulin or a sulfonylurea

The intranasal approach reduces exosome loss by bypassing intestinal and hepatic routes (Guo et al., 2019)