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This study focused on the effects of short-term (5 days) and long-term (14 days) administration of Tesofensine on specific genes in the rat hippocampus, a region of the brain involved in mood regulation

JospeMRoyMBrownRHaszardJMeredith-JonesKFangupoLet alIntermittent fasting, Paleolithic, or Mediterranean diets in the real world: Exploratory secondary analyses of a weight-loss trial that included choice of diet and exercise

The standard approach is optimization first: hydration, electrolyte repletion, and slower dose titration resolve most cases without discontinuation