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BCG vaccination induces long-term functional reprogramming of human neutrophils

However, its important to keep the following in mind: ALA is not a substitute for statins or other prescription cholesterol medications The lipid-lowering effect is generally modest, especially in healthy individuals or those already on treatment Dose and duration matter most benefits are seen at 6001,200mg/day over 8+ weeks Antioxidant and anti-inflammatory effects: moderate evidence ALA is best known for its antioxidant activity and thats not just in theory

doi: 10.1016/j.bioactmat.2022.06.010 95 XueJ.WangJ.FengD.HuangH.WangM

GCH1 is the rate-limiting enzyme for BH4, and the GCH1/BH4 pathway can regulate redox reactions and cell apoptosis, thereby protecting cells from the impact of oxidative stress and mitochondrial damage (83, 84)