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Acknowledgements Work in the authors laboratory has been supported by grants from the NIH (DK57539, DK58282, DK64819 and DK63608-Columbia Diabetes Research Center)

On this basis, this review comprehensively examines the role of ferroptosis in NDDs and explores the mechanisms through which exercise modulates ferroptosis to alleviate NDD pathology, thereby providing a scientific foundation for exercise-based brain health interventions

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