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TRIUMPH-4: Higher discontinuation rates (up to 18.2% at 12 mg)

And thats just a quick snapshot of possible health perks: A study published in 2025 in the journal Nature Medicine linked these medications known as glucagon-like peptide-1 receptor agonists, or GLP-1s to a lower risk of 42 health conditions, including dementia, clotting disorders and addiction

From a public health perspective, if we are working to end the opioid crisis and reduce rates of smoking and excess alcohol consumption, we need treatments that can scale to reach a large portion of the affected population

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