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reported that AEG-1-C75S leads to dysregulation of specific differential gene expression in the hepatic periportal, mid-lobular, and pericentral regions, impairs hepatic metabolic homeostasis, and promotes MASH progression (161)

Their principal advantages include dose-dependent estrogen suppression, fast reversibility of hormone secretion after treatment cessation, oral delivery, and avoidance of the flare-up effect

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Due to its fundamental role in maintaining cellular homeostasis, glutathione remains one of the most widely studied endogenous molecules in redox biology and metabolic research