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This guidance was reinforced through IKS Health coding analysis citing Coding Clinic 3Q 2019, Page 37 and remains active in FY2026 guidelines

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The regulatory pathway for generic small molecules is well-established, straightforward, and relatively inexpensive compared to the biosimilar approval pathway for biologic peptides

Most relevant to this article are the ALDH polymorphisms associated with inborn errors of metabolism disorders, which often include neurological manifestations, such as mental retardation, spasticity, and seizures