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But here's what the trend gets right: our brains ARE being rewired by supernormal stimuli

We found that this modest increase in homocysteine correlated with a decrease in endothelium-dependent vasodilation both in isolated aortic rings as well as in situ mesenteric micro-vessels from CBS +/ mice [59, 61]

(2023) "Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes" The New England Journal of Medicine, 389(24) This article was reviewed by and approved by Alice Fletcher, Lead Bariatric Dietitian, on 3 April 2025