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Zepbound, a GLP-1 receptor agonist, is also a mimetic of a hormone called glucose-dependent insulinotropic polypeptide (GIP)

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188 Conversely, asprosin, interleukin-6 (IL-6), TNF-, and IL-12p70, which are predominantly secreted by visceral adipose tissue, 189 impair insulin signaling in muscle and liver and drive non-alcoholic fatty liver disease 190 via pro-inflammatory mechanisms

"Our clinicians guide patients through the options and adjust plans based on tolerability, progress, and safety." Availability and Getting Started Patients interested in learning whether GLP-1 treatment may be appropriate can begin by completing a brief online assessment [ MEDVi states that most patients receive a decision within hours following physician review