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Li-Huei Tsais group found that cells carrying the variant run their phospholipid pathway poorly and extra choline reversed the defect, a low-risk and mechanism-based option for carriers even though the targeted human trials are not yet in

Figure 4: Eating too much protein from animal products and nuts, along with a lack of B6, B9, or B12 vitamins, can interfere with the recycling of certain amino acids, like methylmalonic acid (MMA), and cause the release of harmful hydrogen sulfide (H2S)

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