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Our studies showed that the effect of liraglutide on body weight was not compromised in vagotomized animals, supporting the concept that GLP-1Rs in the brain, and not gut-to-brain communication, is mostly responsible for the weight loss effect (117)

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Researchers curious about how the amylin pathway is discussed alongside a dual GIP/GLP-1 agonist can read our guide to cagrilintide dosage with tirzepatide