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Based on UK guidelines and common practice, a GP surgery may refuse to give a B12 injection a day earlier than scheduled for a patient with Pernicious Anemia for a few key reasons: Clinical Guidelines and Protocols Standard Treatment Schedules: The NHS and professional bodies like the British Society of Haematology have established guidelines for B12 injections for Pernicious Anemia

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doi: 10.1161/CIRCRESAHA.116.307591 117 HjortebjergRBojsen-MollerKNSoebyMOxvigCMadsbadSFrystykJ