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481 In clinical trials, filgotinib has been shown to improve UC symptoms and reduce intestinal inflammation while reducing the use of hormonal drugs and alleviating the adverse effects of hormonal drugs in patients

Its primary effect is driving neurogenesis in the dentate gyrus, the hippocampal subregion most associated with memory formation and spatial navigation

On another note, someone with severe adrenal insufficiency can experience some of the more severe side effects

L-carnitine, a diet component and organic cation transporter OCTN ligand, displays immunosuppressive properties and abrogates intestinal inflammation