For example, a Vitamin B12 deficiency A lack of RBCs means that not enough oxygen reaches the gut
doi: 10.1186/s13045-024-01559-0 Summary Keywords cancer therapy, ferroptosis, immunometabolism, iron homeostasis, redox signaling, tumor-associated macrophages Citation Qian Z, Zhang Z, Bai W, Li J, Rao X, Huang G, Liu J and Wei W (2026) Immunometabolic crosstalk between tumor- associated macrophages and ferroptotic cancer cells: mechanisms, regulation, and therapeutic applications
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This decline correlates closely with the visible signs of skin aging: loss of firmness, increased fine lines, slower healing, and diminished radiance
