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Combining empagliflozin with other diabetes treatments, such as metformin, sulfonylureas, or insulin, can provide several benefits: Synergistic Effect: Different classes of diabetes medications work through various mechanisms

J Am Soc Nephrol 11(10):19181925 Fdinger M, Buchmayer H, Heinz G, Papagiannopoulos M, Kletzmayr J, Perschl A, Vychytil A, Hrl WH, Sunder-Plassmann G (2001) Association of two MTHFR polymorphisms with total homocysteine plasma levels in dialysis patients