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For women, this becomes even more pronounced around the menstrual cycle

It activates AMPK to induce a shift from anabolic to catabolic metabolism, increases insulin sensitivity, and promotes the secretion of growth/differentiation factors in the intestines and kidneys, thereby reducing dietary intake and lowering blood sugar and weight during pregnancy in patients with PCOS (Dunne et al., 2023

(2013) Ketamine does not produce relief of neuropathic pain in mice lacking the -common receptor (CD131)