Of course, this is all observational
our nails, hair, muscles and skin)
Considering the positive impact of Nrf2 in ameliorating oxidative stress, a number of bioactive components that exert protective effect against APAP-associated hepatotoxicity have been identified and reported, including caffeic acid that activates the Keap1-Nrf2 antioxidant defense system (Pang et al., 2016), carnosic acid that promotes nuclear translocation of Nrf2 (Guo et al., 2016), and esculentoside A that activates Nrf2 via AMP-activated kinase/Akt/glycogen synthase kinase 3 pathway (Wang et al., 2016)
The peptide has been studied extensively across various organ systems, demonstrating cytoprotective effects in the gastrointestinal tract, liver, pancreas, heart, blood vessels, muscle, tendon, ligament, bone, and nervous system