1 In addition, pituitary tumors associated with low gonadotropin production, such as prolactinomas (which produce high amounts of the hormone prolactin and can reduce production of other pituitary hormones), can cause infertility
However, CJC-1295 (especially the DAC version) can cause sustained elevation in IGF-1, whichif mismanagedmay increase the risk of: Insulin resistance Carpal tunnel syndrome Soft tissue growth (in rare, prolonged cases) Pituitary overstimulation That said, these issues are more often associated with excessive dosing or continuous high-frequency use
however, administration is inadvisable in any patient with a known hypersensitivity to levocarnitine or formulation components
After four months, sperm parameters normalized in 69% of those receiving the L-carnitine combination and 22% of those receiving placebo, and after six months, the spontaneous pregnancy rate was almost 24% in the supplement group versus almost 5% in the placebo group