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Figure 7 Discussion Since the pathological process of sepsis-induced multiple organ dysfunction remains incompletely understood, the treatment of sepsis has not significantly changed over the past 40 years ( Gstp / mice showed both the notable higher mortality rate and serum HMGB1 level, as well as severer septic pulmonary injury compared with wild-type mice after CLP surgery

These also show pharmacological properties including immunomodulatory, antidiabetic, antiinflammatory, antihypertensive, anticancer, antioxidant, antimicrobial, antiangiogenic, and enzymatic activity modulation [45]

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346 Additionally, MT overexpression is primarily observed in the invasive ductal carcinoma subtype of BC and is associated with p53 inhibition and resistance to apoptosis