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But higher melanin also means were more prone to: Dark spots that take months to fade Uneven patches and post-acne marks Hyperpigmentation from sun exposure Tan that settles in fast and leaves slow Add to that the daily reality harsh Indian sun, dust, pollution, hard water and your skin is constantly working overtime just to stay normal

10.1016/j.pharmthera.2017.11.001 84

Chemical structures of lipoic acid and lipoyllysine residue The figure illustrates the chemical structures of lipoic acid in its oxidized and reduced forms, its two enantiomers ( R - and S -lipoic acid), and its covalent attachment to a lysine residue of the E2 component of the -ketoacid dehydrogenase complex (and the H protein of the glycine cleavage system), forming a lipoyllysine moiety