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This means oral exposure through nursing carries substantially lower bioavailability than injection in an adult

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Long-term studies are needed to validate the potential cardioprotective effects of low dose GLP-1 in generally healthy individuals A Review on the Efficacy and Safety of Oral Semaglutide PMC What the evidence suggests: Low-dose Semaglutide may reduce the rate of major cardiovascular events and death in patients with metabolic disease

They also have a boxed warning regarding thyroid C-cell tumors observed in rodents (though human relevance remains uncertain)