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EstroGel Side Effects to Know Below are the reported possible side effects of EstroGelthe first two were the most common in clinical trials, and the others are listed in the FDA-approved patient info: headache breast tenderness or pain irregular vaginal bleeding or spotting stomach/abdominal cramps, bloating nausea and vomiting hair loss fluid retention vaginal yeast infection skin irritation at the application site Risks, Precautions, and Who May Not Be a Good Candidate EstroGel is generally well tolerated , but people with certain health histories or symptoms may not be a good candidate for it

If Phase III trials are successful, Novo Nordisk may seek FDA and EMA approval in the next few years

The study also reported inconsistent potency among the compounded tirzepatide samples, with some containing as little as 43 percent of the drug amount listed on the label

The unusual shape and increased thickness can reduce stability, create abnormal motion, and place greater stress on the cartilage during daily activities and sports