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They are not a quick-fix solution on their own

(PubMed) Knekt P, Ritz J, Pereira MA, et al

When semaglutide is added to a stimulant regimen, patients may experience compounded increases in resting heart rate or blood pressure variability throughout the day

However, also dietary/drinking water Se excess is associated with infertility and testicular degeneration in experimental animals, related to higher GPX4 and lactate dehydrogenase activity and higher hydrogen selenide production, and reduced spermatozoa motility, concentration, and typical spermatozoa morphological defects (with the fusion of two midpieces, vacuolization of the cytoplasm, and twisted tails) (85, 105, 117, 169)