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Depletion of CSE elevated RSL3-induced LPO (Fig

One possible explanation is that the anti-inflammatory and neuroimmune effects of GLP-1 receptor activation may occur at lower levels of receptor engagement than the metabolic effects (like weight loss or appetite suppression)

GLP-1 receptor agonists have been shown to reduce systemic inflammation through several mechanisms: Reducing oxidative stress: GLP-1s can reduce oxidative stress, a key contributor to inflammation

[2] Treatment typically starts with 3 mg once daily for 30 days, then increases to 7 mg daily, with a possible further increase to 14 mg if needed for glycaemic control