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Conclusions and Relevance The antidepressant properties and tolerability profile of KET01 in these RCTs, including minimal dissociation and cardiovascular effects, support further development of oral KET01 formulation for at-home administration

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demonstrated that ferritin delivery to lysosomes requires NCOA4, and NCOA4-deficient cells fail to degrade ferritin, leading to a reduction in bioavailable intracellular iron (53)

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