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More recently, the largest systematic review of studies on the association of IGF-1 with the risk of prostate cancer concluded that there is a 21% increased risk of prostate cancer per SD increase in IGF-1, with a stronger association with more aggressive and advanced cases [71]

In a mouse model of inflammation, the decrease of LPS-induced paw edema by DATS was associated with reduced serum concentrations of the pro-inflammatory cytokines, TNF-, IL-6, and monocyte chemotactic protein-1 (MCP-1) (36)

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